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Description
Biotinylated B7-H6/NCR3LG1 Fc&Avi Tag Protein, HumanProduct Specification Species Human Synonyms B7 H6,NCR3LG1,B7 Homolog 6 Accession Q68D85 1 Amino Acid Sequence Target (Asp25 Ser262) with Human IgG1 Fc &Avi Tag at C Terminus Expression System HEK293 Molecular Weight 75 90 kDa (Reducing) Purity 95% by SDS PAGE & 90% by SEC HPLC Endotoxin <0. 1EU g Conjugation Biotin Tag Avi Tag, Human IgG1 Fc Physical Appearance Lyophilized powder Storage Buffer PBS PH7. 4 5% trehalose Reconstitution Reconstitute at
Product Specification
| Species | Human |
| Synonyms | B7-H6,NCR3LG1,B7 Homolog 6 |
| Accession | Q68D85-1 |
| Amino Acid Sequence | Target (Asp25-Ser262) with Human IgG1 Fc &Avi Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 75-90 kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & ＞90% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, Human IgG1 Fc |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS PH7.4 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1. Jin Y, Wang X, Kong W, Li X. Association between elevated serum soluble B7-H6 and infection in hemodialysis patients. Clin Exp Nephrol. 2025 May 27. |
Background
B7-H6, a glycosylated member of the B7 family of immune co-stimulatory proteins, is structured with a 238-amino acid extracellular domain containing one Ig-like V domain and one Ig-like C1 domain, a 21-amino acid transmembrane segment, and a 171-amino acid cytoplasmic domain featuring one ITIM, one SH2, and one SH3 motif. Both Ig-like domains undergo N-linked glycosylation. Notably, B7-H6 is expressed in various primary human tumors, such as leukemia, lymphoma, and gastrointestinal stromal tumors, but it is not constitutively expressed in normal tissues.
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